BMP4 and central nervous system cancer: Supporting the view that DNAm levels can be dynamic in carcinogenic cells, we recently observed such dynamic changes in a time course Illumina 450k DNAm profiling experiment covering 480,000 CpG sites in glioma and normal neural stem cells, both treated at baseline with a BMP (bone morphogenetic protein) differentiation inducing factor (BMP4), and followed up for a maximum of 64 days, with measurements taken at baseline, 8, 16, 32, 48 and 64 days.