SOX11 and coloboma: The prevalence of ocular phenotypes was significantly reduced in the double morphants (sox11 MO: 70.3%±6.7% malformed lens, 75.4%±8.3% coloboma; sox11 + shha MOs: 28.9%±9.2% malformed lens; 34.7%±2.7% coloboma; p<0.0001; Figures 6E and S5C).