To explore this possibility we assessed the effects of Brg1 loss on Wnt-driven adenoma formation by driving recombination of the floxed Apc and Brg1 alleles with the Tg(Cyp1a1-cre/ESR1)1Dwi transgene, further abbreviated as AhCreERT[30]. The gene discussed is CYP1A1; the disease is adenoma.