STAG2 mutation has previously been reported in one Ewing sarcoma tumor and in multiple EFT cell lines [29] and has additionally been reported as a recurrently mutated tumor suppressor gene in other tumor types including glioblastoma, urothelial carcinoma, and acute myeloid leukemia [29], [40]–[44]. Here, STAG2 is linked to acute myeloid leukemia.