In addition, the model was advantageous as it enabled examination of the expression of the HDAC1 and MTA1 genes in all stages of esophageal carcinogenesis, including squamous hyperplasia, squamous dysplasia, squamous cell carcinoma (SCC), Barrett’s esophagus, ADC and adenosquamous carcinoma (ASC). This evidence concerns the gene MTA1 and AIDS dementia complex.