In the present study, the patient was considered to be a cisplatin-refractory case as, following BEP, BVP and VP regimens, the patient experienced complete remission (defined as no residual tumor and a normal serum AFP level) for approximately three months after each treatment (from February 28 to June 4, 2010 and from October 11, 2010 to January 10, 2011). The gene discussed is AFP; the disease is neoplasm.