The immunohistochemical analysis of 96 benign and 108 malignant lesions of the gallbladder revealed that the positive expression of erythropoietin-producing hepatoma-amplified sequence receptor A7 (EphA7) and AEG-1/MTDH is significantly higher in gallbladder adenocarcinoma than in benign lesions (82). Here, MTDH is linked to hepatocellular carcinoma.