SND1 and malignant colon neoplasm: The positive expression of AEG-1/MTDH and SND1 is an independent poor prognostic predictor in colon cancer, as observed by multivariate Cox regression analysis, and the increased expression of AEG-1/MTDH and/or SND1 is closely associated with the carcinogenesis, progression and prognosis of colon cancer (78).