A number of clinical variables and biological markers have been applied over the last decade in predictive models of survival for patients with CHF (5,6), including inflammatory cytokines (7,8) high-sensitivity C-reactive protein (CRP) (9) natriuretic peptides (10,11) neurohormones (12) and oxidative stress (13), all of which are useful for diagnosis and prognosis. This evidence concerns the gene CRP and congestive heart failure.