Patients with a higher RDW significantly differed from the others in terms of age, Hgb, anemia, NYHA classification, left ventricular ejection fraction (LVEF), B-type natriuretic peptide (BNP), lipid profiles [specifically, total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and triglycerides (TG)] blood urea nitrogen (BUN), eGFR, CRP and loop diuretics at presentation. The gene discussed is NPPB; the disease is anemia.