Whilst most prior sources are able to obtain significant results for HRAS, MAP2K1, MAPK1, and RAF1, significant results for half the prior sources for CDK5 and MAPK3 they struggle to provide meaningful information for inference of gene interactions in the context of colorectal cancer with the remaining two knock-downs (MAP2K2 and NGFR). This evidence concerns the gene CDK5 and colorectal cancer.