SSTR5 and pancreatic insulinoma: Moreover, SSTR5 P335L prevents the inhibitory effects of SSTR5 agonist RPL-1980 on cell proliferation of Mia PaCa-2 cells and glucose-stimulated insulin secretion from mouse insulinoma β-TC6 cells, while wild-type SSTR5 enhances the effects (Zhou et al., 2011c).