Based on recently communicated data that IL-6 treatment results in the phosphorylation of Bim at serine 69 and subsequent increases binding of Bim to Mcl-1, it is however still possible that PPP sensitizes MM cells to ABT-737 by post-translational modification of Mcl-1 and/or Bim thus inhibiting protein-protein binding [42]. This evidence concerns the gene BCL2L11 and Miyoshi myopathy.