For the hTERT rs2736098 G>A, the genotyping was successful in 600 (95.39%) ESCC cases and 651 (94.90%) controls in all 1315 samples, and for TERT-CLPTM1L rs401681 C>T, the genotyping was successful in 604 (96.03%) ESCC cases and 664 (96.78%) controls. The gene discussed is TERT; the disease is esophageal squamous cell carcinoma.