Specifically, suppression of β-catenin, signal transducer and activator of transcription3 (STAT3), and CREB-binding protein (CBP) has been shown to prevent the growth and metastasis of glioma [16]–[18], though few studies have examined changes in the expression of miRNAs resulting from these TF-targeted therapeutic interventions. The gene discussed is CREBBP; the disease is glioma.