We analyzed the genome-wide RNA transcript profile from TCGA (breast invasive carcinoma gene expression) by RNAseq data set (TCGA_BRCA_exp_HiSeqV2-2013-12-18) including 1106 samples from breast cancer patients, and found distinct differences in the expression patterns of SOX2 and SOX2OT in breast cancer samples (Heat map, Figure 1C). Here, SOX2 is linked to invasive breast carcinoma.