MiR-874, which has been previously associated with unfavorable prognosis in invasive breast cancer [23] was inversely correlated with several of their paired genes (EZH1, FGD6, PSD4, NFAIC2IP, STAT3, TBRG1, TRIM44, VPS13A, ZNF76), suggesting that miR-874 has a critical role in the regulation of genes preferentially expressed in F-BC, compared with the sporadic cases. The gene discussed is STAT3; the disease is invasive breast carcinoma.