Mcl-1 (myeloid cell leukemia sequence 1) and Bcl-2 (B-cell CLL/lymphoma 2) have been predicted as potential target genes of miR-29 family and both of them belong to Bcl-2 family which play central roles in cell death regulation and alterations in their expression and function contribute to the pathogenesis and progression of human cancers [23]. This evidence concerns the gene MCL1 and cancer.