Recently mutations in ZIP13, a member of the SLC39A/Zrt-Irt-like protein (ZIP) family, have been identified as the cause for the spondylocheiro dysplastic Ehlers–Danlos syndrome (SCD-EDS), a form of EDS sharing some similar clinical presentations with EDS VI, which is caused by mutations in PLOD1 gene encoding lysyl hydroxylase (LH1) (Fukada et al., 2008; Giunta et al., 2008). This evidence concerns the gene PLOD1 and kyphoscoliotic Ehlers-Danlos syndrome.