The decrease in HLTF staining was statistically significant during thyroid tumor progression in terms of both MOD, which corresponds to the mean staining intensity (Kruskall-Wallis: p < 0.0005, Figure 3A), and the LI, which corresponds to the percentage of immunopositive cells (Kruskall-Wallis: p < 10−6, Figure 3B). Here, HLTF is linked to thyroid tumor.