In relation to theprognosis for gallbladder carcinoma, little has been published recently on theprognostic implications of the proteins P531,2,9,23,25, E-cadherin (E-CD)11,24, cyclooxygenase 2(COX-2)10,14 and epidermal growth factor receptor (EGFR)4,6,8,26. This evidence concerns the gene PTGS2 and gallbladder carcinoma.