To investigate if high Sox9 expression is conserved in a GEMM of lung ADC, we stained lung adenoma and ADC sections from the LSL-K-rasG12D lung ADC mouse model for Sox9 and observed Sox9 protein expression to be mostly absent from normal lung and adenoma tissue, but highly expressed in ADC tumors (Fig. 1D). The gene discussed is SOX9; the disease is lung adenoma.