MACC1 and colorectal carcinoma: We stratified our cohort of CRC patients into three groups according to the combination of different MACC1 and β-catenin expression levels: group 1, low MACC1/normal β-catenin expression (n=82); group 2, high MACC1/normal β-catenin expression and low MACC1/abnormal β-catenin expression (n=102); and group 3, high MACC1/abnormal β-catenin expression (n=139).