The LPA receptors are expressed in a wide variety of tissues and cells, including high mRNA expression of LPA1 in the brain [42], LPA2 in a number of cancers [43]–[46], LPA3 in the uterus [47], [48], LPA1 and LPA4 on MAdCAM-1+ endothelial cells [3], LPA5 in the small intestine on CD8+ intraepithelial lymphocytes [49], and LPA6 in hair follicles [50]. Here, LPAR1 is linked to cancer.