In addition to the white matter pathologies, we also report a distinct pathological feature of our mTBI model not previously documented, typified by a reduction in vascular extracellular matrix protein (laminin), an increase in ICAM1+ oligodendroglia like cells in the white matter, and a localized perivascular and periventricular activation of microglial and astroglial cells. The gene discussed is LAMB2; the disease is concussion.