A 314 kb deletion in the Xq26.3 region affecting NHE6 and FHL1 genes in a 2-year-old boy was associated with symptoms of severe intellectual disability, absent speech, ataxia, and epilepsy likely from functional deficits in NHE6, whereas FHL1 gene disruption was associated with later onset of muscular dystrophy (Tzschach et al., 2011). The gene discussed is FHL1; the disease is Intellectual disability.