Instead, the Pathways in cancer genes Kras, Met, Figf, Hgf, Fgf7, Ctnnb1 and Tcf7l1, and directly interacting genes Nr3c2 and Csnk2a1 may lead to new insights in US28-mediated signaling and ultimately the oncomodulatory role of HCMV. The gene discussed is TCF7L1; the disease is cancer.