HLA-A and Whipple disease: Here, we observed an overrepresentation of nine HLA alleles (HLA-A*02, A*68, B*14, B*38, B*39, B*41, C*03, C*08, DQB1*04) (Table 3) in patients with classic Whipple’s disease and subclinical hypothyroidism, but these differences did not reach significance, likely reflecting the small number of patients investigated; thus, a larger cohort could confirm the results of Martinetti et al. [10] regarding HLA and Whipple’s disease and will be necessary to confirm these initial observations regarding an association with subclinical hypothyroidism .