However, in additional analysis in which we constructed models in groups as in Tables 4 and 5 but with adjustment for age, sex, race, and waist circumference as potential confounders, total and HMW adiponectin concentrations remained associated with plaque in patients with abdominal obesity and without joint deformities (P = 0.02 for each relationship). This evidence concerns the gene ADIPOQ and Abdominal obesity.