Their mean age was 72.83 ± 7.01 years (range: 62–78 years); 2 patients had Child class A disease and 8 had Child class B disease.In the RFA group, mean pre-treatment serum AFP level was 130.45 ± 242.65 ng/mL (range: 2.3–779 ng/mL); mean pre-treatment tumor size was 29.42 ± 10.50 mm (range: 17–50 mm); mean post-treatment serum AFP level was 75.76 ± 137.99 ng/mL (range: 2.9–432 ng/mL); and mean survival time was 23.70 ± 21.87 months (range: 1–63 months) (Figure 1). The gene discussed is AFP; the disease is neoplasm.