Therefore, we used mouse GPC3, which shares 95% amino acid sequence identity with human GPC3, established a GPC3 transgenic mouse ovarian cancer cell line, OV2944-HM-1 (HM-1), and used the intraperitoneal ovarian cancer mouse model to analyze immune response in GPC3-expressing mouse ovarian cancer. This evidence concerns the gene GPC3 and ovarian carcinoma.