CD86 and infection: MDCs showed up-regulations of the maturation markers CD80 and CD86 in blood and LN at early time points of primary infection (in blood: p = 0.008 at day 4 pi for CD86 and p = 0.008 at day 2 pi for CD80, in LNs: p = 0.031 at day 9 for CD80) (Figure 2F, G, I and J).