Ferrarese and coworkers [33] showed a decrease in glutamate reuptake by platelets obtained from ALS patients, and Poulopoulou and coworkers [34] found that the expression of the metabotropic glutamate receptor subtype mGLUR2, which is known to provide protection against excitotoxicity, was diminished in ALS T lymphocytes. The gene discussed is GRM2; the disease is amyotrophic lateral sclerosis.