Inflammatory mediators such as C-reactive protein (CRP), interleukin (IL)-6, and tumor necrosis factor (TNF)-α are frequently elevated in patients with type 2 diabetes [4], [5] as well as in the sera of patients many years before the clinical onset of RA [9], suggesting a critical role in the immunopathogenesis of this disease. The gene discussed is IL6; the disease is rheumatoid arthritis.