The infection of cells by several viruses has been shown to activate the ATF6 pathway, including the Tick-borne encephalitic virus, African swine fever virus (ASFV), West Nile virus (WNV), and HCV (Ambrose and Mackenzie, 2011; Merquiol et al., 2011; Galindo et al., 2012; Yu et al., 2013). This evidence concerns the gene ATF6 and infection.