In patients with atopic eczema/dermatitis syndrome, 6-month or 12-month DSW drinking daily 500 mL (hardness 1000 ppm, Mg 100.0 mg, Na 37.0 mg, Ca 35.5 mg, K 34.5 mg, Zn 2.0 μg, Cu 2.2 μg, I 4.5 μg, P 4.5 μg and Se 0.2 μg) significantly decreased the levels of potassium and toxic minerals like mercury and lead and significantly increased the levels of Se [7] and 1-year DSW drinking reduced IgE and serum cytokines including interleukin-4, -13 and -18 levels [8]. The gene discussed is IL4; the disease is atopic eczema.