AKT1 and prostate carcinoma: Major signaling pathways regulating cell growth and death such as nuclear factor-κB (NF-κB) [18], phoshatidylinositole-3 kinase (PI-3 K)/Akt [19, 20], and mitogen-activated protein kinases (MAPK) [21] are activated in prostatic carcinomas [7, 10, 21–30].