Galectin-3 expression was shown to increase migration and/or invasion of many tumor types, such as breast cancer (65), melanoma (14), lung cancer (66), sarcoma (67), gastric cancer (68), and chronic myelogenous leukemia (CML) in vitro (27). The gene discussed is LGALS3; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.