Based on the established role of D. discoideum GbpC protein in chemotaxis and the role of human ROCO proteins in processes related to phagocytosis in response to host infection (MASL1 and LRRK2), it can be speculated that slime molds and placozoa have independently acquired multiple ROCO genes in a process of convergent evolution. Here, MFHAS1 is linked to infection.