A similar regression model constructed for AH showed that leptin levels increased by 2.1 times the risk of hypertension in men (p = 0.003; odds ratio [OR] 2.1; confidence interval [CI] 1.3–3.6) and in women (p = 0.01; OR 1.75; CI 1.2–3.8). This evidence concerns the gene LEP and hypertensive disorder.