We also saw trends for correlations between changes in depression and PPBG (r = 0.46, p = 0.06); positive affect and insulin (r = 0.40, p = 0.08); perceived stress and BMI (r = 0.42, p = 0.06); perceived stress and weight (r = 0.43, p = 0.06); and positive affect and insulin resistance (r = 0.42, p = 0.07). This evidence concerns the gene INS and major depressive disorder.