Furthermore, while less than a quarter of the p53Δ/Δ mice or DicerΔ/Δ, p53wt/Δ mice developed more than a single tumor in the skin, forty-one percent of mice co-ablated for Dicer and p53 in the skin developed multiple simultaneous tumors (Fig. 6B and Table 1). Here, DICER1 is linked to neoplasm.