First, tumor exosomes closely reflect the parental cancer cells and typically carry tumor antigens specific for the tumors that produce and release them, such as Melan A, HER2, Silv, CEA, mesothelin, CD24, and EpCAM, thereby enhancing tumor antigen recognition and priming cytotoxic T cells to induce protective antitumor immune responses [12, 26-28]. Here, EPCAM is linked to neoplasm.