MKI67 and ductal breast carcinoma in situ: In contrast, we found that DCIS lesions in Subgroup IIb, which had the same molecular subtypes as the adjacent IDC but not the same subtypes as the adjacent TDLU, had a higher Ki-67 index (P<10−7) and a higher likelihood of positive p53 staining (P = 0.02), and less p16 staining (P = 0.08, borderline) than those in type I DCIS lesions with different molecular subtypes from the adjacent IDC.