Quantitative expression estimation was performed for eight genes showing high methylation/deletion frequency in ccRCC (LRRN1, GORASP1, IQSEC1, FOXP1, GNAI2, FGD5, PLCL2, and ALDH1L1; Figure 4). The gene discussed is LRRN1; the disease is nonpapillary renal cell carcinoma.