CCDC19-expressing A549 and SPAC1 cells also formed significantly less colonies than those of their respective mock cells in a colony formation assay (P = 0.003 for A549; P = 0.01 for SPCA1; Fig. 2C), suggesting the inhibitory effect of CCDC19 on anchorage-dependent growth of NSCLC cells. Here, CFAP45 is linked to non-small cell lung carcinoma.