In this respect, SH-SY5Y cells, a human neuroblastoma line capable of neurotransmitter biosynthesis [38] and in vitro neuronal dendrite extension, were recently stably transfected with TRPV1 [39,40], but studies with TRPM8 and TRPA1 have not been reported previously. The gene discussed is TRPA1; the disease is neuroblastoma.