Spearman correlation showed that PAF-AH activity correlated positively with TBIL, TBA, ALT, AST, TG, and apoB and negatively with ChE, HDL-c, and apoAI in patients with hepatitis B. Moreover, serum PAF-AH may be used for predicting CSHB and mortality in patients with hepatitis B, and PAF-AH activity was an independent factor predicting CSHB. This evidence concerns the gene GPT and hepatitis B virus infection.