Incidence rates of pneumonia during the 1-year follow-up period were 4.35 (95% CI: 1.89∼9.64) per 100 person-years and 2.14 (95% CI: 1.31∼3.32) per 100 person-years for PC patients who did and those who did not receive treatment with GnRH agonists, respectively. Here, GNRH1 is linked to pachyonychia congenita.