CRP levels and the ESR were significantly correlated with the mRNA levels of IL-10, IL-16, IL-17, and IL-27 in the TB group (CRP: P = 0.018, P = 0.007, P = 0.024, and P = 0.009, respectively; ESR: P = 0.037, P = 0.041, P = 0.003, and P = 0.008, respectively). The gene discussed is IL27; the disease is tuberculosis.