One area of contention is the exact role of cysLTR1 antagonists in the treatment algorithm for asthma, whether this should be as a monotherapy alternative to inhaled corticosteroids (ICS) or as an add-on therapy to corticosteroids instead of long-acting beta-agonists (LABA) and the relative efficacy of the cysLTR1 antagonists compared to these alternative treatment options [50, 79]. Here, CYSLTR1 is linked to asthma.