One recent “real-world” study in asthmatic patients, involving two parallel multicenter pragmatic trials, suggested that cysLTR1 antagonists may be equivalent to ICS as first-line monotherapy and equivalent to LABA as add-on therapy in patients with asthma not controlled on ICS alone, although the authors did recommend caution in the interpretation of the results because of the nature of the studies [80]. Here, CYSLTR1 is linked to asthma.