Our results of the logistic regression analysis and ROC curves suggest that the A-FABP concentration assesses the probability of MetS similarly to or even better than adiponectin and better than leptin in premenopausal women, whereas the adiponectin concentration seems to be a better biomarker for MetS than A-FABP and leptin in postmenopausal women. This evidence concerns the gene ADIPOQ and metabolic syndrome.